磷酸化細(xì)胞周期末期促進(jìn)復(fù)合蛋白APC1抗體（）

英文名稱：Anti-phospho-APC1（Ser688）                            濃度： 1mg/1ml 

抗體來源：Rabbit

克隆類型：polyclonal          

 交叉反應(yīng)： Human, 

產(chǎn)品類型: 一抗  

性    狀:   Lyophilized or Liquid 

保存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

產(chǎn)品介紹 ：This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.

Function : Component of the anaphase promoting complex/cyclosome （APC/C）, a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Subunit : The APC/C is composed of at least 12 subunits. 
Post-translational modifications : Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis.
Similarity : Belongs to the APC1 family.
Contains 4 PC repeats. 

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